site map | search> 
 
Click to register to shop on-lineClick for information on how to contact us.Click for information about who we are.Click for print formatted product literature.Click to fill out our customer satisfaction survey.Click for information on whic trade shows we will be attending.
New Products
Filtration Products
Process Filtration
Process Systems
Laboratory Filtration
Disposable Bag Products
Laboratory Dialysis Products
Labware Products
Cell Culture Products
Chromatography Products
Operating Room Disposables
OEM Products

We are ISO 9001:2000 certified

MicroKros® Modules


Hollow Fiber Modules for Small Volume Filtration and Characterization

Product Searches:



Designed for gentle cross flow filtration of small volumes ranging from 2 - 50 ml, disposable MicroKros Hollow Fiber Modules are the first efficient and practical tangential flow filtration device for R&D volumes in the laboratory setting. While MicroKros modules are typically operated by a peristaltic pump, these devices also offer the unique advantage of manual operation for quick and convenient separations for small volumes. Concentration utilizes two retentate syringes connected to the luer inlet/outlet ports to pass the sample back and forth through the membrane lumen while a third syringe collects the filtrate by way of one of the side-ports. In diafiltration, a fourth syringe can be used to either supply more sample for concentration or buffer for diafiltration via the luer T connector.

QUICK & EFFICIENT FILTRATION

  • 5 - 30 minute Separations
  • 2 modes: Pump Operation & Manual Operation
  • Gentle process for increased viability
  • 90 - 99% Product Purity
  • 85 - 95% Product Recovery

Dimensions:
SA (cm2)Scale LengthID (mm)TL (cm)L (cm)EL (cm)
5-81/3xFL3,510,210,28,0
8-112/3xFL3,514,214,212,2
13-201xFL3,523,223,221,2

Specifications:

Housing:Polysulfone
Inlet/Outlet Ports:Male Luer-Lok (MLL)
Permeate Ports:Female Luer-Lok (FLL)
Potting:Epoxy
Process Volume:2 mL - 60 mL
Surface Area:5 - 20 cm2
Packaging:Dry, pre-wetted or irradiated

3 MembranesFiber IDMWCO
Mixed Cellulose Ester (ME)0,6 mm0,1 µm, 0,2 µm
Polyethersulfone (PES)0,5 mm0,2 µm, 0,5 µm
Polysulfone (PS)1,0 mm100 kD

0,5 mm0,05 µm, 20 nm (500 kD), 100 kD, 50 kD, 10 kD

MicroKros Hand Operation


While MicroKros modules can be operated using a small capacity peristaltic pump, these devices also offer the unique advantage of hand operation for quick and convenient separations of very small volumes. Hand operation utilizes two retentate syringes connected to the luer inlet/outlet ports (by way of Luer T's) to pass the sample back and forth through the membrane lumen. A third syringe is connected to one of the female luer side ports to receive the filtrate as the retentate volume diminishes. A fourth syringe, connected to one of the inlet Luer T's can be used to either supply more sample for concentration or buffer for diafiltration.

ConcentrationDiafiltration

Advantages of Disposability

  • Easier FDA Validation
  • Saves Money & Time
  • No Cross-Contamination
  • Less Down-Time
  • Low Shear
  • Directly Scalable for Production
  • Easy Retrofit for other HF Modules


Applications:

  • Cell Washing
  • Lysate Clarification
  • Bacterial Concentration
  • Micro-particle Diafiltration
  • Macromolecular Isolation
  • Virus Purifications
  • Viral Clarification
  • Protein Purification
  • Antibody Production
  • Desalting & Buffer Exchange
  • NanoParticle Diafiltration

Filtration Resources:










RELATED PRODUCT:

KrosFlo Research II System for volumes 2 - 60 ml
Learn More >

hi dave

    copyright © 1995-2008 SPECTRUM® LABORATORIES, INC All rights reserved