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MiniKros® Plus Modules


Disposable Hollow Fiber Tangential Flow Modules for Process Scale Volumes

Distributed in Europe by JM Separations

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MiniKros Plus offer the same gentle and efficient tangential flow filtration of MiniKros modules, plus the option of 3 different inlet/outlet connection types (1-1/2" Sanitary, 3/4" Sanitary and 1/2" Hose Barb) for increased convenience and flexibility. Perfectly suited for process optimization of 300 mL to 100 liters and scaling filtration applications up to production volumes, the MiniKros Plus module consists of Spectrum's high quality hollow fibers potted in a symmetric housing with two filtrate side ports. The hollow fiber membrane geometry and flow dynamics provide consistent filtration performance, direct scalability for production and high product recovery essential for pharmaceutical and diagnostic process development. All modules are autoclavable or are available irradiated (irr).

Dimensions:
SA (cm2)Scale
Length
ID (mm)TL (cm)L (cm)EL (cm)
600 - 10501xFL18,828,623,520,6
1800 - 38001xFL31,228,623,520,6
3800 - 66002xFL31,248,147,244,0
5700 - 99003xFL31,273,869,065,8

Specifications:

Housing:Clear and Pigmented Polysulfone
Inlet/Outlet Ports:1-1/2" Sanitary, 3/4" Sanitary, 1/2" Hose Barb, 3/8" Hose Barb
Filtrate Ports:3/8" Hose Barb
Potting:Polyurethane
Process Volume:300 mL - 100 L
Surface Area:600 - 9900 cm2
MembraneFiber IDMWCO
Mixed Cellulose Ester (ME)0,6 mm0,2 µm, 0,1 µm
Polyethersulfone (PES)0,5 mm0,5 µm, 0,2 µm
Polysulfone (PS)0,5 mm0,05 µm, 20 nm (500 kD), 100 kD, 50 kD, 10 kD

Advantages of Disposability

  • Easier FDA Validation
  • Saves Money & Time
  • No Cross-Contamination
  • Less Down-Time
  • Low Shear
  • Directly Scalable for Production
  • Easy Retrofit for other HF Modules


Process Development Applications:

  • Diafiltration of Diagnostic Particles
  • Cell Washing and/or Harvesting
  • Clarification of Cellular Debris for Protein or Virus
  • Protein Purification and Concentration
  • Monoclonal Antibody Production
  • Purification and Concentration of Virus
  • NanoParticle Diafiltration

Filtration Resources:









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RELATED PRODUCTS:

MiniKros Plus System
for volumes from 300 ml to 100 liters
Learn More >

MiniKros Pilot System
for volumes 10 to 1000 liters
Learn More >

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